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2.1.4 Extracellular FluidĪ similar argument applies to the Extracellular Fluid. The use of this convention allows predictions to be made about what will happen with various interventions and within limits these are physiologically meaningful.
![human body fluid compartments human body fluid compartments](https://philschatz.com/anatomy-book/resources/2703_Distribution_of_Water_in_the_Human_Body_in_Terms_of_ICF_and_ECF_Pie_Chart.jpg)
Most tissues are water-rich and contain 70-80% water. By the age of 60 years, total body water (TBW) has decreased to only 50% of total body weight in males mostly due to an increase in adipose tissue. Total body water as a percentage of total body weight decreases progressively with increasing age. By the age of 12 months, this has decreased to 60% which is the adult value.
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At birth, the amount of interstitial fluid is proportionally three times larger than in an adult. Neonates contain more water then adults: 75-80% water with proportionately more extracellular fluid (ECF) then adults. 2.1.1 Variations in Water Content Variation due to Age These figures are standard values which are quoted frequently and are average values. The hypothetical adult female contains 55% of her body weight as water: this lower percent being due to a higher fat content. The 70 kg 'standard male' contains 42 liters of water - 60% of his body weight.